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Cell 19, 829840 (2005). 34, 12621270 (2014). Xie, P. et al. Natl Acad. Metab. 8, 512521 (2008). Science 298, 23532358 (2002). J. Lipid Res. The net reaction of bromination follows: To begin removing the impurities, the cholesterol sample (0.97 g) was dissolved in tert-butyl-methyl-ether (7mL). 394, 617626 (2006). Open Access Chem. (NiemannPick type C2). Solved 7-cholesten-3 beta-ol +br2 +ch3cooh - Chegg Sci. Proc. The Bromination of Cholesterol, An Electrophilic Addition Reaction of a Natural Product lab report University Massachusetts College of Pharmacy and Health Sciences Course Organic Chemistry I (CHE 231) 132 Documents Academic year:2018/2019 TT Uploaded byThao Tran Helpful? Biol. Transintestinal cholesterol transport is active in mice and humans and controls ezetimibe-induced fecal neutral sterol excretion. The second part of the mechanism involves reaction of the benzene p-bond with either the Lewis acid-base adduct (shown) or simply with Br to provide a carbocation intermediate.
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